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| Background |
The anti-microbial activity (oligodynamic action) of small quantities of metals, recognized since the nineteenth century, has been the basis for the development of many anti-microbial processes and related products. More recently, silver has been utilized for topical applications, and 1 to 3% silver sulfadiazine cream is used worldwide to prevent the infection of burn wounds and to treat post-infection skin conditions.
12.106 Silver Silver occurs naturally mainly in the form of its very insoluble and immobile oxides, sulfides and some salts. It has occasionally been found in groundwater, surface water and drinking-water at concentrations above 5mg/litre. Levels in drinking-water treated with silver for disinfection may be above 50mg/litre. Recent estimates of daily intake is about 7mg per person. Only a small percentage of silver is absorbed. Retention rates in humans and laboratory animals range between 0 and 10%. The only obvious sign of silver overload is argyria, a condition in which skin and hair is heavily discolored by silver in the tissues. An oral NOAEL for argyria in humans for a total lifetime intake of 10 g of silver was estimated on the basis of human case reports and long-term animal experiments. The low levels of silver in drinking-water, generally below 5mg/litre, are not relevant to human health with respect to argyria. On the other hand, special situations exist where silver salts may be used to maintain the bacteriological quality of drinking-water. Higher levels of silver, up to 0.1 mg/liter (this concentration gives a total dose over 70 years of half the human NOAEL of 10 g), could be tolerated in such cases without risk to health. There are no adequate data with which to derive a health-based guideline value for silver in drinking-water. History of guideline development The 1958, 1963 and 1971 WHO International Standards for Drinking-water did not refer to silver. In the first edition of the Guidelines for Drinking-water Quality, published in 1984, it was not considered necessary to establish a guideline value for silver in drinking-water. No health-based guideline value for silver was proposed in the 1993 Guidelines. Where silver salts are used to maintain the bacteriological quality of 12. CHEMICAL FACT SHEETS 435 drinking-water, levels of silver up to 0.1 mg/liter can be tolerated without risk to health. Assessment date The risk assessment was originally conducted in 1993. The Final Task Force Meeting in 2003 agreed that this risk assessment be brought forward to this edition of the Guidelines for Drinking-water Quality. Principal reference WHO (2003) Silver in drinking-water. Background document for preparation of WHO Guidelines for drinking-water quality. Geneva, World Health Organization (WHO/SDE/WSH/03.04/14).
(2) Desirable: 6.5-8.5 (3) Desirable: 15 mg/l Pt-Co (4) Desirable: less than 75% of the saturation concentration (5) Desirable: 150-500 mg/l (6) Desirable: 0.3 mg/l Assessment dateThe risk assessment was originally conducted in 1993. The Final Task Force Meetingin 2003 agreed that this risk assessment be brought forward to this edition of theGuidelines for Drinking-water Quality.Principal referenceWHO (2003) Selenium in drinking-water. Background document for preparation ofWHO Guidelines for drinking-water quality. Geneva, World Health Organization(WHO/SDE/WSH/03.04/13).12.106 SilverSilver occurs naturally mainly in the form of its very insoluble and immobile oxides,sulfides and some salts. It has occasionally been found in groundwater, surface waterand drinking-water at concentrations above 5mg/litre. Levels in drinking-watertreated with silver for disinfection may be above 50mg/litre. Recent estimates of dailyintake is about 7mg per person.Only a small percentage of silver is absorbed. Retention rates in humans and laboratoryanimals range between 0 and 10%.The only obvious sign of silver overload is argyria, a condition in which skin andhair is heavily discolored by silver in the tissues. An oral NOAEL for argyria inhumans for a total lifetime intake of 10 g of silver was estimated on the basis of humancase reports and long-term animal experiments.The low levels of silver in drinking-water, generally below 5mg/litre, are not relevantto human health with respect to argyria. On the other hand, special situationsexist where silver salts may be used to maintain the bacteriological quality ofdrinking-water. Higher levels of silver, up to 0.1 mg/liter (this concentration gives atotal dose over 70 years of half the human NOAEL of 10 g), could be tolerated in suchcases without risk to health.There are no adequate data with which to derive a health-based guideline value forsilver in drinking-water.History of guideline developmentThe 1958, 1963 and 1971 WHO International Standards for Drinking-water did notrefer to silver. In the first edition of the Guidelines for Drinking-water Quality, publishedin 1984, it was not considered necessary to establish a guideline value for silverin drinking-water. No health-based guideline value for silver was proposed in the 1993Guidelines. Where silver salts are used to maintain the bacteriological quality of12. CHEMICAL FACT SHEETS435drinking-water, levels of silver up to 0.1 mg/liter can be tolerated without risk tohealth.Assessment dateThe risk assessment was originally conducted in 1993. The Final Task Force Meetingin 2003 agreed that this risk assessment be brought forward to this edition of theGuidelines for Drinking-water Quality.Principal referenceWHO (2003) Silver in drinking-water. Background document for preparation ofWHO Guidelines for drinking-water quality. Geneva, World Health Organization(WHO/SDE/WSH/03.04/14).
SilverDYNE® Colloidal Silver is obtained by a combination of a lyophilic colloid formed, and a lyophobic colloid of silver in an aqueous solution. The lyophilic colloid protects the lyophobe making coagulation in the lyophobe more difficult and causing the free silver atoms produced to become predominantly reoxidized to the ionic state.
SilverDYNE®is a clustered distilled water compound, with a double colloidal silver based, stable suspension, non-toxic, non chemical and non-hazardous product, that when used as directed will not only disinfect water, but can also extend the shelf life of most fruits and vegetables without any taste, smell, color, or toxicity. SilverDYNE® is unique because of the way it is engineered. It uses special clustering de-ionized water and engineering process that keeps the silver particles in suspension, for increased absorption and efficiency as well as guided particle direction for the elimination of bacteria. We make true colloidal silver consisting of both elemental and ionic particles providing the ultimate particle surface area and an extremely high efficiency index. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||













